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TRP ion channels in the nervous system [electronic resource] / David Clapham. Details

TRPionchannelsinthenervoussystemelectronicresourceDavidClapham
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TRP ion channels in the nervous system [electronic resource] / David Clapham.

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(CIT): Neurotransmitters, hormones, and pharmacologic agents act by binding specific receptors on the cell surface. Dr. Clapham's lab is interested in how a receptor initiates intracellular events such as the opening of ion channels, the activation of enzymes, or the release of intracellular calcium; and the structures, functions, and relations of receptors, G proteins, ion channels, and calcium. The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to changes in their local environments. TRP channels are found in many eukaryotes, from yeast to mammals. They are a diverse group of proteins organized into six families. In the peripheral nervous system, stimuli including temperature, pressure, inflammatory agents, and receptor activation effect TRP-mediated responses.
Channel: NIH
Video Length: 0s
Date Found: Wed, Sep 17 2008 1:34 PM
Category: Science
Date Produced:
View Count: 29
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