From: WNEM Saginaw on Wed, May 25 2011 8:24 AM

The grand finale of Oprah Winfrey’s 25-year talk show run airs Wednesday, and has fans and stars alike looking back on the cultural icon.

From: WNEM Saginaw on Tue, Jan 25 2011 8:39 AM

Oprah Winfrey reveals a major family secret on her talk show.

From: WNEM Saginaw on Wed, Mar 24 2010 4:37 AM

Oprah Winfrey has settled a defamation lawsuit filed by a headmistress she had accused of performing poorly at her South African girls school, where some students claimed they were abused, lawyers say.

From: WNEM Saginaw on Thu, Jan 28 2010 6:46 PM

Oprah Winfrey interviews Jay Leno, focusing on his late-night war with Conan O’Brien.

From: WNEM Saginaw on Tue, May 05 2009 10:32 PM

Elizabeth Edwards opens up to Oprah Winfrey about whether she still loves her husband, former presidential candidate John Edwards, after his admitted affair.