From: www.ecancer.tv on Tue, Jan 18 2011 6:23 AM

Metastatic breast cancer patients who had circulating tumor cells (CTCs) in their blood before or after high-dose chemotherapy (HDCT) followed by autologous stem cell transplantation had poor outcomes, according to researchers from the University of Texas MD Anderson Cancer Center.Patients with ...

From: www.ecancer.tv on Tue, Jan 18 2011 5:17 AM

The combination of pertuzumab and trastuzumab had superior antitumor activity in women with early HER2-positive breast cancer, according to Phase II study results of the NeoSphere neoadjuvant trial.Details of these study results were presented at the 33rd Annual CTRC-AACR San Antonio Breast Canc...

From: www.ecancer.tv on Tue, Jan 18 2011 5:17 AM

Researchers presented Phase III efficacy data from the GeparQuinto study, a head-to-head comparison of neoadjuvant lapatinib and trastuzumab in combination with chemotherapy for patients with early breast cancer, at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12 2010.

From: www.ecancer.tv on Fri, Jan 14 2011 7:34 AM

Professor John Heath discusses the data he presented at NCRI 2010 on the use of computer science and mathematics to model cancer pathways. Recent advances in the understanding of cancer have revealed that a number of different factors influence how tumours behave and that tumours are frequently c...

From: www.ecancer.tv on Fri, Jan 14 2011 7:34 AM

Prof Robert Weinberg explains what he presented at NCRI 2010 regarding the mechanisms of cancer cells disseminate within the body and the formation of metastases in distant tissues. Although this process appears to be complex, activation of just one normally latent embryonic programme known as e...

From: www.ecancer.tv on Fri, Jan 14 2011 7:34 AM

Prof Mary Gospodarowicz, president-elect of the Union for International Cancer Control (UICC), tells ecancer.tv how she hopes to take the organisation forward during her presidency. One of the strengths of the UICC is the diversity of its membership; its members include governments, patient grou...

From: www.ecancer.tv on Thu, Jan 13 2011 11:00 AM

Prof Gareth Morgan, Dr Faith Davies and Eric Lowe, talking at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics, discuss how the data presented at the meeting will benefit patients being treated for myeloma. The workshop was supported by an unrestricted med...

From: www.ecancer.tv on Tue, Jan 11 2011 2:33 PM

Prof Jonathan Ledermann speaks about the change in opinion towards the retreatment of patients with ovarian cancer. Recent studies have shown that the addition of trabectedin to pegylated liposomal doxorubicin therapy can increase overall survival, particularly in women who are partially platinu...

From: www.ecancer.tv on Tue, Jan 11 2011 9:11 AM

Prof Malcolm Mason discusses the results of an intergroup study - carried out by the UK Medical Research Council (MRC), the National Cancer Institute of Canada (NCIC) and the Southwest Oncology Group (SWOG) from the United States - looking at patients with locally advanced prostate cancer or hig...

From: www.ecancer.tv on Tue, Jan 11 2011 8:08 AM

Prof Alastair Thompson speaks to ecancer.tv a meeting on breast cancer at NCRI 2010. This meeting will look at the role of pathologists, basic scientists, clinicians and surgeons in a truly multidisciplinary approach to cancer care. Prof Thompson discusses the research he carries out in Dundee a...

From: www.ecancer.tv on Tue, Jan 11 2011 8:08 AM

Derek Stewart, a former cancer patient, speaks about his work with the Consumer Liason Group providing a patient perspective for cancer research groups and cancer services. This group allows patients to have involvement in clinical trial design to help the trials appeal to patients. The patients...

From: www.ecancer.tv on Tue, Jan 11 2011 8:08 AM

Prof Gerard Graham talks about the influence of chemokines on the behaviours of cancer cells. Chemokines regulate the movement of blood within the body, but it has been shown that tumour cells adopt these leukocyte navigational properties during metastases, moving to the same parts of the body a...

From: www.ecancer.tv on Tue, Jan 11 2011 8:08 AM

Prof Pamela Rabbitts talks about the Leeds Institute of Molecular Medicine and the work she has been doing on lung cancer and head and neck cancer. These two cancers show a number of similarities but head and neck cancer is much more accessible for research, especially in the precancer stage. Pr...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

Dr Herve Avet-Loiseau, presenting at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics, talks about the use of genomic testing to predict survival rates of myeloma patients and to predict which patients will benefit from which drugs. He also talks about typ...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

Dr Perkins, talking at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics discusses the work of the Multiple Myeloma Research Foundation (MMRF), whose main focus is to accelerate the development of therapeutics for myeloma patients. The MMRF provides grants ...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

Dr Lonial, presenting at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics, talks about novel clinical trials designs particularly for melanoma. He discusses the importance of trial designs which give patients faster and less toxic doses of treatment.The wo...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

The Co-Chairs (Dr Ken Anderson, Dr Jesus San Miguel, Dr Nikhil Munshi, Dr Keith Stewart) of the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics discuss the highlights of the meeting, focussing on the genetics and pharmacogenomics of multiple myeloma and the ...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

Dr Fonseca, talking at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics, discusses the occurrence of hypomethylation in myeloma and genomic prognostic modules for the disease.The workshop was supported by an unrestricted medical education grant from the fo...

From: www.ecancer.tv on Tue, Jan 11 2011 6:04 AM

Dr Chapman, speaking at the IV International Workshop on Myeloma Genetics, Pharmacogenomics & Novel Therapeutics, discusses the findings of a large genome sequencing project and the future implications. The project found genes mutations found in other cancer appear in myeloma, meaning that exist...

From: www.ecancer.tv on Tue, Dec 28 2010 7:32 AM

Dr Paul Lorigan explains what the construction of the new patient treatment centre at The Christie NHS foundation Trust will mean to clinicians. The new facilities will reduce waiting times, allow the delivery of the very best treatments to more patients more efficiently and the development of i...