From: NIH on Tue, Sep 16 2008 7:00 PM

From: NIH on Tue, Sep 16 2008 7:00 PM

The Stem Cell Interest Group was established to enhance communication and to foster collaboration among scientists from varying disciplines interested in stem cells. Topics of interest include fundamental stem cell biology, ontogeny, gerontology, and the therapeutic potential of stem cells. The S...

From: NIH on Tue, Sep 16 2008 6:59 PM

(CIT): The first speaker for the Immunology Interest Group 2001 Fall series is Leslie Berg, Professor in the Department of Pathology, University of Massachusetts Medical School, Worcester, MA. Dr. Berg has done ground-breaking work using in vivo models to study the role of the T cell antigen rece...

From: NIH on Tue, Sep 16 2008 6:59 PM

From: NIH on Tue, Sep 16 2008 6:59 PM

(CIT): For more information about the speaker, visit The Stem Cell Interest Group was established to enhance communication and to foster collaboration among scientists from varying disciplines interested in stem cells. Topics of interest include fundamental stem cell biology, ontogeny, geront...

From: NIH on Tue, Sep 16 2008 6:58 PM

(CIT): The research in Dr. Weaver's laboratory concerns the mechanisms by which CD4 T cells control adaptive immunity. Major current projects are: the generation and characterization of transgenic and knock-in mouse models for tracking T cell fate during CD4 effector and memory T cell develo...

From: NIH on Tue, Sep 16 2008 6:58 PM

From: NIH on Tue, Sep 16 2008 6:58 PM

(CIT): Over the last several years biochemical approaches have been highly effective in detailing receptor-triggered signaling pathways in immune cells. However, biochemical approaches have severe limitations in investigations of the earliest events in ligand-mediated immune receptor activation ...

From: NIH on Tue, Sep 16 2008 6:57 PM

From: NIH on Tue, Sep 16 2008 6:57 PM

(CIT): David's lab is interested in better understanding the immuno-regulatory mechanisms that govern the initiation, regulation, and development of immune effector responses following infection with pathogens of the gastrointestinal tract. Trichuris muris is one of the model systems his lab...

From: NIH on Tue, Sep 16 2008 6:56 PM

(CIT): The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an annual Immunology...

From: NIH on Tue, Sep 16 2008 6:56 PM

(CIT): Dr. Lowell's work has focused on the role of Src-family tyrosine kinases in regulating many signaling pathways, including responses to innate immune stimuli (bacterial LPS, DNA or yeast), cytokines, growth factors or immune complexes in myeloid cells and B-lymphocytes. In recent work,...

From: NIH on Tue, Sep 16 2008 6:56 PM

(CIT): Dr. Dennis Klinman was among the first to identify and characterize immunostimulatory DNA oligonucleotides. Dr. Klinman headed the Section of Viral Immunology at the Center for Biologics Evaluation and Research of the FDA before joining the Cancer and Inflammation Program, Laboratory of Ex...

From: NIH on Tue, Sep 16 2008 6:53 PM

(CIT): Both during his work with Harald von Boehmer and more recently as an independent investigator, Iannis made seminal contributions to the study of early T cell development. More recently, he became interested in the study of Notch-induced T leukemogenesis. Hematopoietic Stem Cell (HSC) self-...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): Aberrations in protein phosphorylation due to kinase (or phosphatase) mutation or overexpression leads to dysregulation of cellular signaling and has been linked to a variety of pathologies, including cancer, autoimmune, and metabolic disorders. Quantification of specific phosphorylation s...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): Mass spectrometry and database searching is widely used for protein identification. The proteins in the sample are first separated to obtain a mixture of the proteins of interest. These protein mixtures are then digested with a proteolytic enzyme. The masses of the resulting peptides and t...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): Stem cells can self-renew and differentiate along multiple lineages to generate different tissues. In the embryo, multipotent stem cells respond to various cues to undergo morphogenesis and produce these tissues. The epidermis of the skin is an excellent model to explore how multipotent st...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): The concept of a default mode of brain function arose out of a focused need to explain the appearance of activity decreases in functional neuroimaging data when the control state was passive visual fixation or eyes closed resting. The problem was particularly compelling because these acti...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): The development of fluorescent proteins as molecular tags over the past decade has splurred a revolution by allowing complex biochemical processes to be correlated with the functioning of proteins in livings cells. Fluorescent proteins such as green fluorescent protein (GFP) from the jelly...

From: NIH on Tue, Sep 16 2008 6:47 PM

(CIT): Professor Shokat received his Ph.D. in 1991 from UC Berkeley and completed post-doctoral work at Stanford in 1994 when he moved to Princeton University as an Assistant Professor of Chemistry and Molecular Biology becoming a tenured Associate Professor in 1998. In 1999, Shokat moved to th...